Levothyroxine Sodium Impurity 14 - Names and Identifiers
Levothyroxine Sodium Impurity 14 - Physico-chemical Properties
Molecular Formula | C14H10I2O4
|
Molar Mass | 496.04 |
Density | 2.156±0.06 g/cm3(Predicted) |
Melting Point | 223.5-225.0 °C(Solv: water (7732-18-5); acetic acid (64-19-7)) |
Boling Point | 527.8±50.0 °C(Predicted) |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | Off-White to Pale Brown |
pKa | 4.10±0.10(Predicted) |
Storage Condition | 2-8°C |
Levothyroxine Sodium Impurity 14 - Upstream Downstream Industry
Levothyroxine Sodium Impurity 14 - Introduction
3,5-diiodothyroacetic ACID, also known as 3,5-diiodothyroacetic acid, is an organic compound.
Nature:
-Appearance: White or light yellow crystal
-Melting point: 220-222 ° C
-Molecular formula: C10H7I2O4
-Molecular Weight: 472.97
Use:
3,5-Diiodothyroacetic acid is a thyroid hormone. It is mainly used in scientific research as a non-selective thyroxine antagonist, which can interfere with the action of thyroid hormones. It can also be used as an intermediate in the preparation of other drugs.
Method:
A commonly used preparation method is through the iodination reaction of p-hydroxyphenoxybenzoic acid, and then acetylation to obtain 3,5-diiodothyroacetic acid.
Safety Information:
3,5-Diiodothyroacetic acid is relatively stable under proper handling and storage conditions. However, it is still a toxic compound and should be used with caution. During operation, wear appropriate protective equipment, such as laboratory gloves, eye protection glasses, etc. When using or handling the compound, follow relevant safety practices and ensure proper ventilation.
Last Update:2024-04-09 20:45:29